The Phagovet project is devised to satisfy market demand for a more secure and reliable solution to control Salmonella and E. coli infections in poultry farms.
Antibiotics have been routinely used in the animal production to promote animal growth or prevent outbreaks of disease. However, its excessive use is associated with the emergence of resistant strains, limiting its therapeutic efficacy and increasing antimicrobial resistance, being a big problem in both human and animal medicine.
Bacteriophages have been used for nearly a century as antimicrobial agents and can be used to reduce the prevalence of pathogenic bacteria. The efficacy of these viruses as antibacterial agents has been amply demonstrated in the literature, both in vivo and in vitro.
Poultry products were undoubtedly the most used meats to study the efficacy of bacteriophage, namely in Salmonella biocontrol in foods. In addition, several reports from case studies investigated the use of virulent bacteriophage to control Salmonella and E. coli infections in birds. These studies have shown that the routine use of phage cocktails can provide an effective and sustainable solution for the control of bacterial populations at various stages of the food chain: from housekeeping to food in food processing facilities.
Nevertheless, in Europe the use of bacteriophages in the control of bacterial infections is still limited mainly due to the lack of legislation that meets the criteria and specificities making it difficult to register and commercialize bacteriophage-based products.
The Phagovet project (funded under the “H2020-EIC-FTI-2018-2020 (FAST TRACK TO INNOVATION (FTI)) proposes the development of a cost-effective, efficient and reliable solution for the control of Salmonella and E. coli infections in poultry farms, based on bacteriophage technology. Phagovet products will consist on a biocide and two technological food additive products based on selected bacteriophages able to kill the target bacteria. These will be the first phage-based solutions to control both bacteria in poultry production while avoiding side effects and residues associated to antibiotic use. Phagovet products will be the first phage-based solution to naturally and effectively control both bacteria in poultry production while avoiding side effects and residues associated to antibiotic use. Thus, Phagovet provides a promising effective control measure for a concerning problem for poultry farmers and for human health.
Saiba mais sobre este projeto em www.phagovet.eu